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Chemical Agents > Tabun >
Emergency Response Card: Information for First Responders - Nerve Agent: Tabun

NERVE AGENT

 

CAS # 77-81-6
RTECS #
Counter Terrorism Card 0002

TABUN
GA

dimethylphosphoramidocyanidic acid, ethyl ester
Ethyl N,N-dimethylphosphoramidocyanidate
Chemical Formula C5H11N2O2P
Molecular mass: 162.12

 

 

TYPES OF
HAZARD/
EXPOSURE

ACUTE HAZARDS/
SYMPTOMS

PREVENTION

FIRST AID/
FIRE FIGHTING

FIRE

React with steam or water to produce toxic and corrosive vapors.

Contain to prevent contamination to uncontrolled areas.

Water mist, fog, and foam, CO2. Avoid methods that will cause splashing or spreading.

EXPLOSION

May result in the formation of hydrogen cyanide.

 

 

EXPOSURE

Liquid or vapors can be fatal.

Clothing releases agent for about 30 minutes after contact with vapor.

Contaminated surfaces present long-term contact hazard.

Do not breathe fumes.
Skin contact must be avoided at all times.

Seek medical attention Immediately.

INHALATION

Inhalation can cause symptoms in 2-5 minutes.

Same sequence of symptoms despite the route of exposure:

MILD

runny nose

tightness of the chest and breathing difficulty

eye pain, dimness of vision and pin pointing of pupils (miosis)

difficulty in breathing and cough

MODERATE

increased eye symptoms with blurred vision

drooling and excessive sweating

severe nasal congestion

increased tightness of the chest and breathing difficulty

nausea, vomiting, diarrhea, and cramps

generalized weakness, twitching of large muscle groups

headache, confusion, and drowsiness

SEVERE

involuntary defecation and urination

very copious secretions

twitching, jerking, staggering and convulsions

cessation of breathing, loss of consciousness, coma and death.

Hold breath until respiratory protective mask is donned.

Fire-fighting personnel should wear full protective clothing and respiratory protection during fire-fighting and rescue.

Positive pressure, full face piece, NIOSH-approved self-contained breathing apparatus (SCBA) will be worn.

If severe signs, immediately administer, in rapid succession, all three Nerve Agent Antidote Kit(s), Mark I injectors (or atropine if directed by a physician).

If signs and symptoms are progressing, use injectors at 5 to 20 minute intervals. (No more than 3 injections unless directed by medical personnel.)

Maintain record of all injections given.

Give artificial respiration if breathing has stopped. Use mouth-to-mouth when mask-bag or oxygen delivery systems not available. Do not use mouth-to-mouth if face is contaminated.

Administer oxygen if breathing is difficult.

SKIN

See Inhalation

Lethal doses can kill in 1-2 hours.

Pupil size may range from normal to moderately reduced.

Protective Gloves: Butyl Rubber Glove M3 and M4 Norton, Chemical Protective Glove Set

The primary mode for decontamination of chemical agents is soap and water. A 0.5% hypochlorite solution can be used. There are differing guidelines for decontamination and more research is needed to identify the optimal decontamination method.

See "Personal Decontamination" and "Appendix D" in Treatment of Chemical Agent Casualties and Conventional Military Chemical Injuries (from the U.S. Navy Counterproliferation Office).

See also the Medical Management of Chemical Casualties Handbook (from the U.S. Army Medical Research Institute of Chemical Defense [USAMRICD]) for a general review of the issues and more on the military decontamination powder approach.

EYES

See Inhalation

Very rapid onset of symptoms (less than 2-3 minutes).

Chemical goggles and face shield.

Immediately flush eyes with water for 10-15 minutes, then don respiratory protective mask.

INGESTION

See Inhalation

Pupil size may range from nomal to moderately reduced.

 

Do not induce vomiting. First symptoms are likely to be gastrointestinal. Immediately administer Nerve Agent Antidote Kit, Mark I.

 

DECONTAMINATION

SPILLAGE DISPOSAL

PACKAGING & LABELLING

  • solids, powders and solutions containing various types of bleach (NaOCl or Ca(OCl)2)
  • DS2 (2% NaOH, 70% diethylenetriamine, 28% ethylene glycol monomethyl ether)
  • towelettes moistened with NaOH dissolved in water, phenol, ethanol, and ammonia
  • Order of preference for decon: aqueous NaOH, Decontaminating Agent (DS2), Sodium Carbonate, and Supertropical Bleach Slurry (STB).

Cover with vermiculite, diatomaceous earth, clay, fine sand, sponges, and paper or cloth towels. Scoop decontaminated material and place in approved container. Treat decontaminant solution with excess bleach to destroy the HCN. After sealing, decontaminate the exterior and label. All leaking containers will be over packed with sorbent (e.g. vermiculite) placed between the interior and exterior containers. Label and dispose according to regulations. Conduct general area monitoring.

Proper Shipping Name: Toxic liquids, organic, n.o.s.
DOT Hazard Class: 6.1, Packing Group I, Hazard Zone B
DOT Label: Poison
DOT Marking: Toxic liquids, organic, n.o.s. (Ethyl dimethylphosphoramidocyanidate) UN 2810, Inhalation Hazard
DOT Placard: Poison

NFPA 704 Signal:

  • Health - 4
  • Flammability - 1
  • Reactivity - 1
  • Special - 0

 

 

 

 


I
M
P
O
R
T
A
N
T

D
A
T
A

PHYSICAL STATE; APPEARANCE:

Colorless to brown liquid, faintly fruity odor. Odorless in pure form.

The industrial product has a brownish color and odor reminiscent of bitter almonds due to the formation of hydrogen cyanide.

May contain 5-20 percent chlorobenzene as solvent and stabilizer.

PHYSICAL DANGERS:


CHEMICAL DANGERS:
Decomposes within 3 months at 65C. Complete decomposition in 195 minutes at 150C. May produce hydrogen cyanide (HCN), oxides of nitrogen, oxides of phosphorus, and carbon monoxide.

OCCUPATIONAL EXPOSURE LIMITS (OELs):
TLV : 0.0001 mg/m3 (military, not ACGIH)

ROUTES OF EXPOSURE:
The substance can be absorbed into the body by all routes.

INHALATION RISK:
Usually liquid in normal state, but will volatilize if heated to form vapor or aerosol.

EFFECTS OF SHORT-TERM EXPOSURE:
Tabun, an organophosphorus compound, is a lethal cholinesterase inhibitor similar in action to GB (Sarin), although only about half as toxic by inhalation.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Limited data suggest delayed neuropathy (postural sway, psychomotor performance). Miosis has been noted up to 62 days.

PHYSICAL
PROPERTIES

melting point: -50C
boiling point: 246C
vapor pressure (20C): 0.07 mm Hg
density (20C):1.077 g /cm3

aqueous solubility (no temperature provided): 0.5 g/ L
aqueous solubility (20C): 72 g /L
estimated log Kow: -1.4
flashpoint: 78C (Closed Cup Method)

ENVIRONMENTAL
DATA

Rapidly hydrolyzed in basic solutions, e.g., Na2CO3, NaOH, or KOH with a half-life of 1.5 minutes at pH 11 at 25C.
Tabun and its hydrolysis products exhibit no significant phototransformations in sunlight.
Tabun and its hydrolysis products are thermally stable at temperatures less than 49C.

N O T E S

 

 

ADDITIONAL INFORMATION

Trade Names and Other Synonyms:

  • Ethyl dimethylphosphoramidocyanidate
  • Dimethylaminoethoxy-cyanophosphine oxide
  • Dimethylamidoethoxyphosphoryl cyanide
  • Ethyldimethylaminocyanophosphonate
  • Ethyl ester of dimethylphosphoroamidocyanidic acid
  • Ethyl phosphorodimethylamidocyanidate
  • EA1205

 

 

IMPORTANT NOTICE:

TABUN (CTC: 0002)    Neither the CDC or NIOSH nor any person acting on behalf of the CDC or NIOSH is responsible for the use which might be made of this information. This card contains the collective views of these agencies and may not reflect in all cases all the detailed requirements in response to a terrorism event on the subject. The user should verify compliance of the cards with the relevant STATE or TERRITORY legislation before use. NIOSH, CDC 2000

 

 

 

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Page last modified August 11, 2003

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